ORN R-0006 1mg
货号：
130-104-439 基本售价：
询价 规格：
EA
产品信息
概述| 货号 | 130-104-439 |
| 描述 | TLR7 and TLR8 are members of the Toll-like-receptor (TLR) family, recognizing (virally derived) double- or single-stranded RNA, leading to activation of immune cells. ORN R-0006 activates both human TLR7 and TLR8 as well as murine TLR7 and induces a broad spectrum of cytokines from human PBMCs (IFN-α, IFN-γ, IL-12, and TNF-α).3 |
性能| 供应商 | Miltenyi |
| 背景 | TLR7 and TLR8 are members of the Toll-like-receptor (TLR) family recognizing pathogen-associated molecular patterns.1,7 The natural ligands of TLR7 and TLR8, double- or single-stranded RNA, can be mimicked by short synthetic oligoribonucleotides (ORNs).2-5 RNA motifs activating either TLR7 or TLR8 only or both, TLR7 and TLR8, have been described. |
