(±)19(20)-DiHDPA
货号：
10007001-1mg 基本售价：
13524.0 元 规格：
1 mg
产品信息
概述| 货号 | 10007001-1mg |
| 描述 | Docosahexaenoic acid (DHA; Item No. 90310) is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain.1 (±)19(20)-DiHDPA is one of the major metabolites produced when DHA is incubated with NADPH-supplemented rat liver microsomes.2 DHA is also slowly metabolized by monkey seminal vesicles to (±)19(20)-DiHDPA.3 The route of production likely proceeds through cytochrome P450-catalyzed epoxidation at the ω-3 double bond, followed by conversion to the vicinal diols by epoxide hydrolase.2,3 |
| 别名 | (±)19,20-DiHDoPE; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Salem, N.,Kim, H.Y., and Yergey, J.A. Docosahexaenoic acid: Membrane function and metabolism. Health effects of polyunsaturated fatty acids in seafoods 263-317 (1986).
2.VanRollins, M.,Baker, R.C.,Sprecher, H., et al. Oxidation of docosahexaenoic acid by rat liver microsomes. J. Biol. Chem. 259(9), 5776-5783 (1984).
3.Oliw, E.H., and Sprecher, H.W. Metabolism of polyunsaturated (n-3) fatty acids by monkey seminal vesicles: Isolation and biosynthesis of omega-3 epoxides. Biochimica et Biophysica Acta 1086, 287-294 (1991).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 362.5 |
| 分子式 | C22H34O4 |
| 稳定性 | ≥ 1 year |
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