8,12-iso-iPF2α-VI-d11
货号:
10006878-50ug 基本售价:
9828.0 元 规格:
50 ug
产品信息
概述货号 | 10006878-50ug |
描述 | 8,12-iso-isoprostane F2α-VI-d11(8,12-iso-iPF2α-VI-d11) contains 11 deuterium atoms at the 16, 16, 17, 17, 18, 18, 19, 19, 20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of 8,12-iso-iPF2α-VI by GC- or LC-mass spectrometry. The relative abundance of deuterium atoms incorporated into each molecule has not been determined. Cayman certifies that less that 1% of the product has no deuterium incorporation (<1% d0). Isoprostanes are non-enzymatic, non-cyclooxygenase prostanoid products of peroxidative damage to membrane lipids.1 Among the many isoprostane isomers, 8,12-iso-iPF2α-VI has been demonstrated to be one of the predominant isomers formed and is also present in urine as one of the major isoprostane products.28,12-iso-iPF2α-VI-d11 is a deuterated internal standard for use in isoprostane quantitation by mass spec modalities. The compound is diastereomeric at C-5, but is otherwise an optically active, single enantiomer. |
别名 | 8,12-epi-iPF2α-VI-d11; |
性能供应商 | Cayman |
应用文献 |
1.Diaz, M.N.,Frei, B.,Vita, J.A., et al. Antoixidants and atherosclerotic heart disease. New England Journal of Medicine 337, 408-416 (1997). 2.Lawson, J.A.,Li, H.,Rokach, J., et al. Identification of two major F2 isoprostanes, 8,12-iso- and 5-epi-8,12-iso-isoprostane F2α-VI, in human urine. The Journal of Biological Chemisty 273, 29295-29301 (1998).
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运输条件 | Dry ice in continental US; may vary elsewhere |
存放说明 | -80 |
纯度 | ≥99% deuterated forms (d1-d11) |
计算分子量 | 365.6 |
分子式 | C20H23D11O5 |
稳定性 | ≥ 1 year |
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