ODN 2088 Control (ODN 2087) 1mg
货号:
130-105-940 基本售价:
询价 规格:
EA
产品信息
概述货号 | 130-105-940 |
描述 | TLR7/8/9 antagonists consist of short single-stranded oligodeoxynucleotides. They can inhibit CpG ODN-mediated activation of TLR9 and/or activation of TLR7/8. ODN 2088 Control (ODN 2087) is a TLR7/8 antagonist, but also acts as a TLR9 antagonist control. The sequence does not form G-Tetrads. |
性能供应商 | Miltenyi |
背景 | TLR7, TLR8 and TLR9 are prominent members of the Toll-like-receptor (TLR) family recognizing pathogen-associated molecular patterns recognizing nucleic acids 3. Activation of these TLRs can be inhibited by short single-stranded synthetical oligodeoxyribonucleotides (ODNs) 4,6. Several classes of and motifs for inhibitory ODN have been identified 1,6,7. |