ODN 2216 1mg
货号：
130-100-244 基本售价：
询价 规格：
EA
产品信息
概述| 货号 | 130-100-244 |
| 描述 | Oligodeoxyribonucleotides containing CpG motifs (CpG ODNs) are widely used for activation of immune cells, such as human PBMCs, murine splenocytes or isolated immune cells, e.g., B cells and pDCs. They also activate signalling in TLR9-expressing recombinant cell lines. ODN 2216 is an A-class ODN for activation of pDCs, induction of IFN-α secretion from PBMCs, and activation of IFN signalling pathways. |
性能| 供应商 | Miltenyi |
| 背景 | TLR9 is a prominent member of the toll-like-receptor (TLR) family recognizing pathogen-associated molecular patterns. TLR9 recognizes specifically unmethylated CpG motifs in bacterial DNA leading to activation of immune cells1,2. These effects can be mimicked by short synthetical oligodeoxyribonucleotides (ODNs) containing unmethylated CpG motifs3. |
