ODN 2395 Control (ODN 5328) 1mg
货号:
130-100-109 基本售价:
询价 规格:
EA
产品信息
概述货号 | 130-100-109 |
描述 | CpG ODNs are widely used for activation of immune cells or induction of signalling in TLR9-expressing recombinant cell lines. Control compounds which contain GpC dinucleotides instead of CpGs are useful to control for the CpG specificity of this effects. |
性能供应商 | Miltenyi |
背景 | TLR9 is a prominent member of the toll-like-receptor (TLR) family recognizing pathogen-associated molecular patterns. TLR9 recognizes specifically unmethylated CpG motifs in bacterial DNA leading to activation of immune cells1,2. These effects can be mimicked by short synthetical oligodeoxyribonucleotides (ODNs) containing unmethylated CpG motifs3. |