CAY10465
货号:
10006546-50mg 基本售价:
8330.0 元 规格:
50 mg
产品信息
概述货号 | 10006546-50mg |
描述 | The aryl hydrocarbon receptor (AhR) is a ligand-dependent intracellular transcription factor whose ligands include some of the most infamous xenobiotics, including dioxin, benzo[a]pyrene, and numerous polyaromatics from soot and coal tar.1 CAY10465 is an analog of resveratrol acting as a potent and selective aryl hydrocarbon receptor agonist, with a Ki of 0.2 nM.2 CAY10465 is inactive as a ligand for the estrogen receptor even at 100 µM. |
性能供应商 | Cayman |
应用文献 |
1.Denison, M.S., and Nagy, S.R. Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals. Annual Reviews of Pharmacology and Toxicology 43, 309-334 (2003). 2.de Medina, P.,Casper, R.,Savouret, J.F., et al. Synthesis and biological properties of new stilbene derivatives of resveratrol as new selective aryl hydrocarbon modulators. Journal of Medicinal Chemistry 48, 287-291 (2005).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 317.1 |
分子式 | C15H9Cl2F3 |
CAS号 | 688348-33-6 |
稳定性 | ≥ 2 years |
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