p53 Product Pack
货号：
10005291-1ea 基本售价：
7182.0 元 规格：
1 ea
产品信息
概述| 货号 | 10005291-1ea |
| 描述 | The Cayman p53 Product Pack contains PRIMA-1, a p53 re-activator that restores the apoptotic activity of mutant p53 via conformational modulation.1 Included in the p53-PAK is Cayman’s p53 (Phospho-Ser392) Polyclonal Antibody (Item No. 10004807), as well as (±)-Nutlin-3 (Item No. 10004372), a p53 activator working via inhibition of p53/Mdm2 binding.2 Cayman’s Caylin-2 (Item No. 10005002), a nutlin analog with growth enhancing properties at low concentrations that are opposite those of (±)-nutlin-3.3 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Bykov, V.J.N.,Issaeva, N.,Shilov, A., et al. Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound. Nature Medicine 8(3), 282-288 (2002).
2.Vassilev, L.T.,Vu, B.T.,Graves, B., et al. In vivo activation of the p53 pathway by small-molecule antagonists of MDM2. Science 303, 844-848 (2004).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 稳定性 | ≥ 1 year |
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