Reversine
货号：
10004412-25mg 基本售价：
6860.0 元 规格：
25 mg
产品信息
概述| 货号 | 10004412-25mg |
| 描述 | Terminal differentiation of embryonic progenitor cells to form distinct, adult tissues is the hallmark of organogenesis in complex organisms. However, in mammals including humans, this process is not readily reversible. Reversine is a 2,6-disubstituted purine derivative that was identified using a screening system based on the loss of terminal differentiation markers in C2C12 myoblast cells.1 Cultured myoblasts treated for four days with 5 µM reversine were dedifferentiated into confluent stem cell progenitors, that could then be induced by osteogenic or adipogenic medium to re-differentiate into bone or adipose precursors, respectively. Reversine is thus an important tool for the study of the control of cell fate. |
性能| 供应商 | Cayman |
| 应用文献 |
1.Chen, S.,Zhang, Q.,Wu, X., et al. Dedifferentiation of lineage-committed cells by a small molecule. Journal of the American Chemical Society 126, 410-411 (2004).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 393.5 |
| 分子式 | C21H27N7O |
| CAS号 | 656820-32-5 |
| 稳定性 | ≥ 2 years |
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