12(S)-HEPE
货号：
32550-100ug 基本售价：
6300.0 元 规格：
100 ug
产品信息
概述| 货号 | 32550-100ug |
| 描述 | 12(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 12-LO. Unstimulated neutrophils metabolize 12(S)-HEPE to 12(S),20-diHEPE, whereas stimulated neutrophils produce 5(S),12(S)-HEPE via the 5-lipoxygenase pathway.1 The competitive action of 12(S)-HEPE with arachidonic acid as a substrate for 5-LO in the formation of leukotrienes may provide a basis for the anti-inflammatory potential of ω-3 fatty acids. |
性能| 供应商 | Cayman |
| 应用文献 |
1.von Schacky, C.,Marcus, A.J.,Safier, L.B., et al. Platelet-neutrophil interactions. 12S,20- and 5S,12S-dihydroxyeicosapentaenoic acids: Two novel neutrophil metabolites from platelet-derived 12S-hydroxyeicosapentaenoic acid. Journal of Lipid Research 31, 801-810 (1990).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 318.5 |
| 分子式 | C20H30O3 |
| CAS号 | 116180-17-7 |
| 稳定性 | ≥ 1 year |
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