(±)16-HETE
货号：
10010635-100ug 基本售价：
6048.0 元 规格：
100 ug
产品信息
概述| 货号 | 10010635-100ug |
| 描述 | Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. (±)16-HETE is the racemic version of a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation. The biological activity of 16-HETE is stereospecific. 16(R)-HETE dose-dependently stimulates vasodilation of the rabbit kidney, however 16(S)-HETE does not affect perfusion pressure.1 At a concentration of 2 µM the (S)-enantiomer of 16-HETE inhibits proximal tubule ATPase activity by as much as 60%, whereas the (R)-isomer has negligible effects on ATPase activity.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Carroll, M.A.,Balazy, M.,Margiotta, P., et al. Cytochrome P-450-dependent HETEs: Profile of biological activity and stimulation by vasoactive peptides. American Journal of Physiology 271, R863-R869 (1996).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 320.5 |
| 分子式 | C20H32O3 |
| CAS号 | 128914-46-5 |
| 稳定性 | ≥ 1 year |
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