StemMACS Nurr1 (NR4a2) mRNA, human
货号：
130-104-384 基本售价：
询价 规格：
EA
产品信息
概述| 货号 | 130-104-384 |
| 描述 | StemMACS™ Nurr1 (NR4a2) encodes the human transcription factor Nurr1 for transient transfection. |
性能| 供应商 | Miltenyi |
| 背景 | The transcription factor Nurr1 is a member of the steroid-thyroid hormone-retinoid receptor superfamily. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophrenia, and manic depression. Nurr1 induces the expression of tyrosine hydroxylase (TH), a critical factor for differentiation into dopaminergic neurons. In pluripotent stem cell research, Nurr1 has been used in combination with other transcription factors (e.g. Mash1, Lmx1a) to promote dopaminergic neuron differentiation. |
