5(S),6(R)-DiHETE
货号：
35200-25ug 基本售价：
1204.0 元 规格：
25 ug
产品信息
概述| 货号 | 35200-25ug |
| 描述 | 5(S),6(R)-DiHETE is a dihydroxy polyunsaturated fatty acid and a nonenzymatic hydrolysis product of leukotriene A4(LTA4). Mouse liver cytosolic epoxide hydrolase catalyzes the conversion of LTA4 to 5(S),6(R)-DiHETE.1 It is a weak LTD4 receptor agonist in guinea pig lung membranes.2 It induces guinea pig ileum contraction with an ED50 value of 1.3 µM.2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Haeggström, J.,Wetterholm, A.,Hamberg, M., et al. Enzymatic formation of 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid: Kinetics of the reaction and stereochemistry of the product. Biochimica et Biophysica Acta 958, 469-476 (1988).
2.Muller, A.,Rechencq, E.,Kugel, C., et al. Comparative biological activities of the four synthetic (5,6)-diHETE isomers. Prostaglandins 38, 635-644 (1989).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 336.5 |
| 分子式 | C20H32O4 |
| CAS号 | 82948-88-7 |
| 稳定性 | ≥ 1 year |
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