TC-E-5003
货号:
14099 基本售价:
1015.0 元 规格:
50 mg
产品信息
概述货号 | 14099 |
描述 | Selective protein arginine methyltransferase 1 (PRMT1) inhibitor (IC50 = 1.5 µM) . Displays no activity against CARM1 and Set7/9 methyltransferases. Inhibits growth of MCF7 breast cancer cells and LNCaP prostate cancer cells. Blocks androgen-induced gene expression in LNCaP cells (ref1). |
别名 | N,N-(Sulfonyldi-4,1-phenylene)bis(2-chloroacetamide) |
性能供应商 | Active Motif |
运输条件 | Blue Ice |
存放说明 | Store desiccated as supplied at -20°C for up to 2 years. Store solutions at -20°C for up to 1 month. |
纯度 | >98% (TLC); NMR (Conforms) |
计算分子量 | 401.3 |
分子式 | C16H14Cl2N2< |
CAS号 | 17328-16-4 |
外观 | White powder. May be dissolved in DMSO (50 mg/ml); DMF (50 mg/ml); Ethanol (nil). |
参考文献 | 1. EM Bissinger et al. Bioorg. Med. Chem. Lett. 2011, 19:3717
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参考图片Chemical structure of TC-E-5003. |