5(S),6(R)-7-trihydroxymethyl Heptanoate
货号：
10005032-1mg 基本售价：
630.0 元 规格：
1 mg
产品信息
概述| 货号 | 10005032-1mg |
| 描述 | Lipoxins are trihydroxytetraene metabolites derived from arachidonic acid through an interaction between lipoxygenases with C-5 and C-15 specificities. Lipoxin A4(LXA4) inhibits the chemotactic responsiveness of polymorphonuclear (PMN) neutrophils to leukotriene B4 and to the peptide formyl-methionyl-leucyl-phenylalanine (fMLP).1 5(S),6(R)-7-trihydroxymethyl Heptanoate is a C-7 truncated analog of lipoxin A4(LXA4) that is equiactive as LXA4 in the inhibition of leukotriene B4(LTB4)-induced polymorphonuclear neutrophils (PMN) chemotaxis with an IC50 value of 5nM.1 |
| 别名 | BML-111; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Lee, T.H.,Lympany, P.,Crea, A.E.G., et al. Inhibition of leukotriene B4-induced neutrophil migration by lipoxin A4: Structure-function relationships. Biochemical and Biophysical Research Communications 180(3), 1416-1421 (1991).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 192.2 |
| 分子式 | C8H16O5 |
| CAS号 | 78606-80-1 |
| 稳定性 | ≥ 1 year |
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