| 货号 | 10006487-1000mg |
| 描述 | Estrogens direct the development of the female genotype in embryogenesis and at puberty. Estradiol is the major estrogen secreted by the premenopausal ovary.1,2 Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position. It is often used in combination with a progestin to induce estrus in domestic livestock.3 Estradiol benzoate binds to the human and murine estrogen receptor α (ERα), and chicken ER with IC50 values in the range of 22-28 nM.4 This reflects a 6-10 fold reduction in binding affinity compared to estradiol.4 |
| 别名 | β-Estradiol Benzoate;17β-Estradiol 3-Benzoate;17β-Oestradiol Benzoate;E2Benzoate; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Miller, W.L., and Tyrrell, J.B. The adrenal cortex. Endocrinology and Metabolism 3rd edition, 555-711 (1995). 2.Vance, D.E. Cholesterol and related derivatives. Biochemistry 2nd ed., 725-748 (1988). 3.Cavalieri, J.,Hepworth, G., and Macmillan, K.L. Ovarian follicular development in Holstein cows following synchronisation of oestrus with oestradiol benxoate and an intravaginal progesterone releasing insert for 5-9 days and duration of the oestrous cycle and concentrations of progesterone following ovulation. Animal Reproduction Science 81, 177-193 (2004). 4.Matthews, J.,Celius, T.,Halgren, R., et al. Differential estrogen receptor binding of estrogenic substances: A species comparison. Journal of Steroid Biochemistry and Molecular Biology 74, 223-234 (2000). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 376.5 |
| 分子式 | C25H28O3 |
| CAS号 | 50-50-0 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |