| 货号 | 10006627-25g |
| 描述 | Saturated fatty acids are synthesized by both plants and animals from acetyl coenzyme A as a form of long-term energy storage. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of the normal human dietary fat intake. Palmitic acid also makes up approximately 25% of the total plasma fatty acids in plasma lipoproteins.1 Saturated free fatty acids induce the expression of cyclooxygenase-2, and after protein acylation, are used to confer lipid anchoring to a variety of signaling molecules.2,3,4,5,6 |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Santos, M.J.,López-Jurado, M.,Llopis, J., et al. Influence of dietary supplementation with fish oil on plasma fatty acid composition in coronary heart disease patients. Annuals of Nutrition and Metabolism 39, 52-62 (1995). 2.Lee, J.Y.,Sohn, K.H.,Rhee, S.H., et al. Saturated fatty acids, but not unsaturated fatty acids, induced the expression of cyclooxygenase-2 mediated through toll-like receptor 4. The Journal of Biological Chemisty 276(20), 16683-16689 (2001). 3.Dietzen, D.J.,Hastings, W.R., and Lublin, D.M. Caveolin is palmitoylated on multiple cysteine residues. Palmitoylation is not necessary for localization of caveolin to caveolae. The Journal of Biological Chemisty 270, 6838-6842 (1995). 4.Robinson, L.J., and Michel, T. Mutagenesis of palmitoylation sites in endothelial nitric oxide synthase identifies a novel motif for dual acylation and subcellular targeting. Proceedings of the National Academy of Sciences of the United States of America 92, 11776-11780 (1995). 5.Topinka, J.R., and Bredt, D.S. N-terminal palmitoylation of PSD-95 regulates association with cell membranes and interaction with K+ channel Kv1.4. Neuron 20, 125-134 (1998). 6.Miggin, S.M.,Lawler, O.A., and Kinsella, B.T. Palmitoylation of the human prostacyclin receptor. Functional implications of palmitoylation and isoprenylation. The Journal of Biological Chemisty 278(9), 6947-6958 (2003). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | >98% |
| 计算分子量 | 256.4 |
| 分子式 | C16H32O2 |
| CAS号 | 57-10-3 |
| 稳定性 | ≥ 2 years |
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