N-Arachidonoyl Taurine
货号：
10005537-500ug 基本售价：
476.0 元 规格：
500 ug
产品信息
概述| 货号 | 10005537-500ug |
| 描述 | Several different arachidonoyl amino acids, including N-arachidonoyl dopamine (NADA) and N-arachidonoyl-L-serine (ARA-S), have been isolated and characterized from bovine brain.1 During mass spectrometry lipidomics analysis of rat brain, a series of fatty acyl amides of a third amino acid, taurine, was discovered.2 This novel class or compounds is present in kidney and activates members of the transient receptor potential (TRP) family of calcium channels.3 N-arachidonoyl taurine, a prominent N-acyl taurine, activates both TRPV1 and TRPV4 with EC50 values of 28 and 21 µM, respectively.3 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Huang, S.M.,Bisogno, T.,Petros, T.J., et al. Identification of a new class of molecules, the arachidonyl amino acids, and characterization of one member that inhibits pain. The Journal of Biological Chemisty 276(46), 42639-42644 (2001).
2.Cravatt, B.F., and Maxey, K.M. . (2004).
3.Saghatelian, A.,McKinney, M.K.,Bandell, M., et al. A FAAH-regulated class of N-acyl taurines that activates TRP ion channels. Biochemistry 45(30), 9007-9015 (2006).
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| 运输条件 | Dry ice in continental US; may vary elsewhere |
| 存放说明 | -80 |
| 纯度 | ≥98% |
| 计算分子量 | 411.6 |
| 分子式 | C22H37NO4S |
| CAS号 | 119959-65-8 |
| 稳定性 | ≥ 1 year |
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