Oleic Acid-2,6-diisopropylanilide
货号：
10006782-5mg 基本售价：
378.0 元 规格：
5 mg
产品信息
概述| 货号 | 10006782-5mg |
| 描述 | AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol.1 Oleic acid-2,6-diisopropylanilide is an inhibitor of acylCoA:cholesterol acyltransferase with an IC50 of 7 nM.2 When co-administered to rabbits or rats fed a high fat, high cholesterol diet, oleic acid-2,6-diisopropylanilide decreased low density lipoproteins and elevated high density lipoprotein levels when administered at 0.05%. |
性能| 供应商 | Cayman |
| 应用文献 |
1.Suckling, K.E., and Stange, E.F. Role of acyl-CoA: Cholesterol acyltransferase in cellular cholesterol metabolism. Journal of Lipid Research 26, 647-671 (1985).
2.Roth, B.D.,Blankley, C.J.,Hoefle, M.L., et al. Inhibitors of acyl-CoA: Cholesterol acyltransferase. 1. Identification and structure-activity relationship of a novel series of fatty acid anilide hypocholesterolemic agents. Journal of Medicinal Chemistry 35, 1609-1617 (1992).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 441.7 |
| 分子式 | C30H51NO |
| CAS号 | 140112-65-8 |
| 稳定性 | ≥ 1 year |
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