γ-Linolenic Acid methyl ester
货号：
10006579-50mg 基本售价：
350.0 元 规格：
50 mg
产品信息
概述| 货号 | 10006579-50mg |
| 描述 | Polyunsaturated fatty acids (PUFAs) are essential nutrients that show distinct deficiency syndromes when not present in adequate amounts in the diet.1,2 γ-Linolenic Acid methyl ester (Methyl GLA) is an esterified version of the free acid which is less water soluble but more amenable for the formulation of GLA-containing diets and dietary supplements. GLA is an ω-6 fatty acid which can be elongated to arachidonic acid for endogenous eicosanoid synthesis. It is a weak leukotriene B4(LTB4) receptor antagonist, inhibiting [3H]-LTB4 binding to porcine neutrophil membranes with a Ki of 1 µM.3 GLA produces 53% inhibition at a 1 mg/kg dose in an in vivo model of LTB4-induced bronchoconstriction.3 |
| 别名 | Methyl GLA;Methyl γ-Linolenate; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Simopoulos, A.P. Omega-3 Fatty acids in health and disease and in growth and development. American Journal of Clinical Nutrition 54, 438-463 (1991).
2.Holman, R.T. Control of polyunsaturated acids in tissue lipids. Journal of the American College of Cardiology 5, 183-211 (1986).
3.Yagaloff, K.A.,Franco, L.,Simko, B., et al. Essential fatty acids are antagonists of the leukotriene B4 receptor. Prostaglandins, Leukot. Essent. Fatty Acids 52(5), 293-297 (1995).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 292.5 |
| 分子式 | C19H32O2 |
| CAS号 | 16326-32-2 |
| 稳定性 | ≥ 1 year |
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