Genistein
货号：
10005167-100mg 基本售价：
336.0 元 规格：
100 mg
产品信息
概述| 货号 | 10005167-100mg |
| 描述 | Genistein is an isoflavonoid phytoestrogenic compound found in soybeans, pea pods, and other legumes. The estimated human normal dietary intake of genistein, primarily as glycosides, is 0 to 0.5 mg/kg. Genistein is present in much greater amounts in nutritional supplements. Genistein is carcinogenic in female neonatal mice, inducing endocrine-dependent uterine tumors in a fashion similar to diethylstilbestrol (DES).1 Genistein is a tyrosine-specific inhibitor of protein kinase activity, blocking the tyrosine-phosphorylation of histone H2B.2 In adult animals, dietary genistein has chemopreventive effects on breast, prostate, and other endocrine-dependent tumors.3 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Newbold, R.R.,Banks, E.P.,Bullock, B., et al. Uterine adenocarcinoma in mice treated neonatally with genistein. Cancer Research 61, 4325-4328 (2001).
2.Akiyama, T.,Ishida, J.,Nakagawa, S., et al. Genistein, a specific inhibitor of tyrosine-specific protein kinases. The Journal of Biological Chemisty 262(1), 5592-5595 (1987).
3.Lamartiniere, C.A.,Cotroneo, M.S.,Fritz, W.A., et al. Genistein chemoprevention: Timing and mechanisms of action in murine mammary and prostate. Journal of Nutrition 132, 552S-558S (2002).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 270.2 |
| 分子式 | C15H10O5 |
| CAS号 | 446-72-0 |
| 稳定性 | ≥ 2 years |
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