Diethylstilbestrol
货号：
10006876-1000mg 基本售价：
280.0 元 规格：
1 g
产品信息
概述| 货号 | 10006876-1000mg |
| 描述 | Diethylstilbestrol (DES) is a synthetic estrogen receptor agonist that was prescribed to pregnant women in the late 1930s. It was banned in 1971 because of possible links to increased risk of breast cancer in mothers along with congenital abnormalities and increased risk of cancer in offspring.1 DES is structurally related to, and is as potent as, estradiol in most assays, with a longer half-life. It has a relative binding affinity to sex hormone binding globulin (SHBG) of 0.2 compared to estradiol which has a relative binding affinity of 100. A concentration of 20 µM DES, displaces 30 ± 13% of 3H-estradiol from SHBG in serum.1,2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Coelingh Bennink, H.J.T. Are all estrogens the same? Maturitas 47, 269-275 (2003).
2.Jury, H.H.,Zaxharewski, T.R., and Hammond, G.L. Interactions between human plasma sex hormone-binding globulin and xenobiotic ligands. Journal of Steroid Biochemistry and Molecular Biology 75, 167-176 (2000).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 268.4 |
| 分子式 | C18H20O2 |
| CAS号 | 56-53-1 |
| 稳定性 | ≥ 2 years |
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