| 货号 | 10004161-10mg |
| 描述 | Diets high in fiber contain plant lignan species that may be directly responsible for some observed health benefits of these diets.1 Luteolin is a polyphenolic flavone found in many plants including soybeans and perilla leaves.2 Luteolin is one of the most potent flavanoid inhibitors of soybean and reticulocyte 15-lipoxygenases, with an IC50 of 0.6 µM.3 Luteolin has also been found to inhibit the release of TNFα from neutrophils, and to inhibit matrix metalloproteinases.4 |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Morton, L.W.,Caccetta, R.A.A.,Puddey, I.B., et al. Chemistry and biological effects of dietary phenolic compounds: Relevance to cardiovascular disease. Clinical and Experimental Pharmacology and Physiology 27, 152-159 (2000). 2.Ueda, H.,Yamazaki, C., and Yamazaki, M. Luteolin as an anti-inflammatory and anti-allergic constituent of Perilla frutescens. Biological and Pharmaceutical Bullentin 25(9), 1197-1202 (2002). 3.Sadik, C.D.,Sies, H., and Schewe, T. Inhibition of 15-lipoxygenases by flavonoids: Structure-activity relations and mode of action. Biochemical Pharmacology 65, 773-781 (2003). 4.Sartor, L.,Pezzato, E.,DellAica, I., et al. Inhibition of matrix-proteases by polyphenols: Chemical insights for anti-inflammatory and anti-invasion drug design. Biochemical Pharmacology 64, 229-237 (2002). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 286.2 |
| 分子式 | C15H10O6 |
| CAS号 | 491-70-3 |
| 稳定性 | ≥ 2 years |
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