CAY10448
货号：
10005633-1mg 基本售价：
224.0 元 规格：
1 mg
产品信息
概述| 货号 | 10005633-1mg |
| 描述 | Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicumpepper.1 Capsaicin signals are transduced by a heat-activated ion channel, the vanilloid receptor 1 (VR1), or transient receptor potential vanilloid 1 (TRPV1).2 CAY10448 is an iodinated nonivamide, a potent capsaicin receptor antagonist with an IC50 value of approximately 10 nM.3 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Gannett, P.M.,Nagel, D.L.,Reilly, P.J., et al. The capsaicinoids: Their separation, synthesis, and mutagenicity. The Journal of Organic Chemistry 53(5), 1064-1071 (1988).
2.Caterina, M.J.,Schumacher, M.A.,Tominaga, M., et al. The capsaicin receptor: A heat-activated ion channel in the pain pathway. Nature 389, 816-824 (1997).
3.Daddario, N.,Minassi, A.,Appendino, G., et al. The taming of capsaicin. Synthesis and vanilloid antagonistic activity of isosteric and regioisomeric halononiv amides and their products of halogen-carbon exchange. 14th Annual Symposium on the Cannabinoids 137-137 (2004).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 433.3 |
| 分子式 | C18H28INO3 |
| CAS号 | 1177195-52-6 |
| 稳定性 | ≥ 2 years |
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