Oleoyl Ethyl Amide
货号：
10005459-1mg 基本售价：
154.0 元 规格：
1 mg
产品信息
概述| 货号 | 10005459-1mg |
| 描述 | Numerous analogs of fatty acyl ethanolamides potentiate the intrinsic biological activity of arachidonoyl ethanolamide (anandamide; AEA).1 This potentiation is ascribed either to inhibition of AEA reuptake into neurons, or inhibition of fatty amide acyl hydrolase (FAAH) within the neurons.2 Oleoyl ethyl amide (OEtA) has potent FAAH inhibitory activity (IC50 5.25 nM in rat brain homogenates) but does not inhibit acidic PEAase or bind to CB1 or CB2 receptors. OEtA is therefore a selective FAAH inhibitor with potential analgesic and anxiolytic activity.3 |
| 别名 | OEtA;N-Ethyloleamide; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Khanolkar, A.D., and Makriyannis, A. Structure-activity relationships of anandamide, an endogenous cannabinoid ligand. Life Sciences 65, 607-616 (1999).
2.Deutsch, D.G.,Glaser, S.T.,Howell, J.M., et al. The cellular uptake of anandamide is coupled to its breakdown by fatty-acid amide hydrolase. The Journal of Biological Chemisty 276(10), 6967-6973 (2001).
3.Vandevoorde, S.,Lavandhomme, P.,Fowler, C.J., et al. Oleoylethylamide, an analgesic FAAH inhibitor which modulates endogenous anandamide, oleoylethanolamide, and 2-arachidonoylglycerol levels in the brain. 14th Annual Symposium on the Cannabinoids 15-15 (2004).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 309.5 |
| 分子式 | C20H39NO |
| CAS号 | 85075-82-7 |
| 稳定性 | ≥ 1 year |
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