Ketoprofen
货号：
10006661-1000mg 基本售价：
112.0 元 规格：
1 g
产品信息
概述| 货号 | 10006661-1000mg |
| 描述 | Non-steroidal anti-inflammatory drugs (NSAIDs) are inhibitors of cyclooxygenase-1 (COX-1) and/or COX-2, and are widely used to treat inflammation and pain. Ketoprofen is a non-selective NSAID exhibiting IC50 values of 0.5 µM and 2.33 µM for human recombinant COX-1 and COX-2, respectively.1 It is supplied as a racemic mixture. The R-enantiomer is the more active isomer, effectively blocking COX activity without increasing inflammatory cytokine production.2 |
| 别名 | Orudis;Oruvail;2-(3-benzoylphenyl)propionic Acid; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Barnett, J.,Chow, J.,Ives, D., et al. Purification, characterization and selective inhibition of human prostaglandin G/H synthase 1 and 2 expressed in the baculovirus system. Biochimica et Biophysica Acta 1209, 130-139 (1994).
2.Ghezzi, P.,Melillo, G.,Meazza, C., et al. Differential contribution of R and S isomers in ketoprofen anti-inflammatory activity: Role of cytokine modulation. Journal of Pharmacology and Experimental Therapeutics 287, 969-974 (1998).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 254.3 |
| 分子式 | C16H14O3 |
| CAS号 | 22071-15-4 |
| 稳定性 | ≥ 2 years |
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