概述| 货号 | RDC0826 |
| 别名 | CRACM1; CRACM1ORAT1; FLJ14466; ORAI calcium release-activated calcium modulator 1; ORAT1; Protein orai-1; TMEM142A; TMEM142Acalcium release-activated calcium modulator 1; Transmembrane protein 142Acalcium release-activated calcium channel protein 1 |
全称 | ORAI Calcium Release-activated Calcium Modulator 1 | | 反应种属 | Mouse |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 84876 (Human); 109305 (Mouse) |
| 背景 | Orai1 is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. Orai1 is a pore subunit of Ca(2+) release-activated Ca(2+) CRAC channels, and STIM1 acts as an endoplasmic reticulum (ER) Ca(2+) sensor that detects store depletion. This type of channel is the primary way for calcium influx into T-cells. Defects in Orai1 are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | |
