概述货号 | RDC0629 |
别名 | IP; MGC102830; PGI receptor; PGI2 receptor; PRIPR; prostacyclin receptor; prostaglandin I2 (prostacyclin) receptor (IP); Prostaglandin I2 receptor; Prostanoid IP receptor |
全称 | Prostaglandin I2 Receptor | 反应种属 | Mouse |
性能供应商 | R&D Systems |
Entrez Gene IDs | 5739 (Human); 19222 (Mouse); 292661 (Rat) |
背景 | PTGIR is a member of the G protein-coupled receptor family 1 and has been shown to be a receptor for prostacyclin (prostaglandin I2 or PGI2). Isoprenylation does not influence ligand binding but is required for efficient coupling to the effectors adenylyl cyclase and phospholipase C. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to PTGIR. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 | - Bioactive Lipid G Protein-Coupled Receptors
- Coagulation
- Eicosanoids and Regulators
- Platelets
- Prostanoids and Receptors
- Steroid Hormones and Bioactive Lipids
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