概述货号 | RDC0782 |
别名 | epithelial membrane protein 2; MGC9056; Protein XMP; XMP; XMPEMP-2 |
全称 | Epithelial Membrane Protein 2 | 反应种属 | Mouse |
性能供应商 | R&D Systems |
Entrez Gene IDs | 2013 (Human); 13731 (Mouse); 360468 (Rat) |
背景 | Epithelial membrane protein-2 (EMP2), a tetraspan protein known to associate with and modify surface expression of certain integrin isoforms, was identified as a prognostic biomarker in human endometrial cancer. EMP2 is expressed in the majority of ovarian tumors and may be a feasible drug target in vivo. EMP2 in several cell types plays a role in growth control, invasion, metastasis, and protein trafficking. It can associate with integrin alpha v beta 3 and FAK, and promote integrin-mediated FAK-Src activation. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 | - Cancer Biomarkers
- Integrins and Associated Molecules
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