概述| 货号 | RDC1599 |
| 别名 | class II cytokine receptor CRF2/12; CRF2/12; CRF2-12; Cytokine receptor class-II member 12; Cytokine receptor family 2 member 12; IFN-lambda R1; IFN-lambda receptor 1; IFN-lambda-R1; IFNLR; IFNLR1; IL-28 receptor subunit alpha; IL-28R1; IL28RA; IL-28RA; IL-28R-alpha; Interferon lambda receptor 1; interferon lambda, receptor 1; interleukin 28 receptor A; interleukin 28 receptor, alpha (interferon, lambda receptor); interleukin 28 receptor, alpha; interleukin or cytokine receptor 2; interleukin-28 receptor subunit alpha; LICR2; Likely interleukin or cytokine receptor 2 |
全称 | Interleukin 28 Receptor alpha | | 反应种属 | Mouse |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 163702 (Human); 242700 (Mouse); 362628 (Rat) |
| 背景 | IL-28 receptor alpha subunit, also named interferon-lambda R1, is a type I transmembrane glycoprotein that is cytokine receptor family 2 member 12 (CRF2-12). It pairs with the IL-10 receptor beta subunit (IL-10 R beta, CRF2-4) to form the IL-28 R. This receptor interacts with the interferon-like cytokines (type III interferons) IL-28A (IFN-lambda 2), IL-28B (IFN-lambda 3) and IL-29 (IFN-lambda 1). Signaling through IL-28 R alpha results in upregulated expression of MHC class I antigens and anti-viral, anti-proliferative and anti-tumor activity. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - IL-10/Interferon Family
- Receptors in the Jak/STAT Pathway
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