概述| 货号 | RDC1361 |
| 别名 | beta receptor10; human interferon alpha; human interferon alpha/beta receptor; IFNABR; IFN-alpha binding protein; IFN-alpha/beta receptor 2; IFN-alpha-REC; IFNAR2; IFNARB; IFN-R; IFN-R-2; interferon (alpha, beta and omega) receptor 2; Interferon alpha binding protein; interferon alpha/beta receptor 2; interferon-alpha/beta receptor beta chain; Type I interferon receptor 2 |
全称 | Interferon alpha/beta Receptor 2 | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 3455 (Human); 15976 (Mouse) |
| 背景 | IFN-alpha/beta R2, also known as IFNAR2, is a 100 kDa component of the class II cytokine receptor that binds the type I interferons IFN-alpha, IFN-beta, and IFN-omega. IFN-alpha/beta R2 associates with the 125 kDa IFN-alpha/beta R1 component to form a receptor complex that transmits antiviral and antiproliferative signals. Down-regulation of the receptor is accomplished by ubiquitination and degradation. A soluble form of the protein, corresponding to the extracellular ligand-binding domain, is generated by alternative splicing. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Cytokines and Receptors in Angiogenesis
- IL-10/Interferon Family
- Receptors in the Jak/STAT Pathway
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