Human CD96 (NP 937839) VersaClone cDNA ( )
货号：
RDC1617 基本售价：
2825.6 元 规格：
10 ug
产品信息
概述| 货号 | RDC1617 |
| 别名 | CD96 antigenMGC22596; CD96 molecule; CD96; DKFZp667E2122; T cell-activated increased late expression protein; TACTILE; TACTILEincreased late expression; T-cell surface protein tactile |
| 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 10225 (Human); 84544 (Mouse); 498079 (Rat) |
| 背景 | CD96 (also Tactile) is a 160 kDa member of the Ig-Superfamily. It is expressed on CD4+ and CD8+ T cells, plus NK cells and select B cells. Human CD96 binds to CD155 and presumably participates in NK cell killing of CD155-expressing target cells. Mature human CD96 is a 564 amino acid (aa), type I transmembrane glycoprotein. It contains a 498 aa extracellular region (aa 22-519) that contains three Ig-like domains. The two N-terminal domains are V-type (aa 38-238), while the distal domain is a C-type structure (aa 269-375). There is one isoform that shows a deletion of aa 183-192. This deletion converts the second V-type domain into an I-like domain, and generates the most common form of CD96. An additional isoform shows the same deletion coupled to a nine aa substitution for aa 410-585. Over aa 1-536, human CD96 shares 59% aa identity with mouse CD96. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Acute Myeloid Leukemia
- Cancer Biomarkers
- Cancer Stem Cell Markers
- Co-stimulatory and Co-inhibitory Molecules
- Leukocyte Receptors/Markers in Allergy and Asthma
- Nectin and Nectin-like Binding Receptors and Ligands
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