Human B7-2/CD86 (NP 787058) VersaClone cDNA (10 UG)
货号：
RDC0693 基本售价：
2825.6 元 规格：
10 ug
产品信息
概述| 货号 | RDC0693 |
| 别名 | Activation B7-2 antigen; B70; B7-2 antigen; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; CD28LG2B7-2 antigen); CD86 antigen; CD86 molecule; CD86; CTLA-4 counter-receptor B7.2; FUN-1; LAB72; MGC34413; T-lymphocyte activation antigen CD86 |
| 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 942 (Human); 12524 (Mouse); 56822 (Rat) |
| 背景 | B7-2/CD86 and the related B7-1/CD80 are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. B7-2 is highly expressed on activated antigen presenting cells and vascular endothelial cells. It binds to CD28 on T cells to enhance T cell activation. It additionally binds CTLA-4 which inhibits the T cell response and supports regulatory T cell function. The relative participation of B7-1 and B7-2 in T cell co-stimulation can alter the Th1/Th2 bias of the immune response. Both B7-1 and B7-2 serve as cellular receptors for B species adenoviruses. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Acute Lymphoblastic Leukemia
- B Cell Activation
- B Cell Markers
- Common Macrophage Markers
- Control of Immune Responses via CD28 and CTLA-4
- Co-stimulatory and Co-inhibitory Molecules
- Co-stimulatory Molecules Associated with Tfh Cells
- CTLA-4: Hiding in Plain Sight
- Dendritic Cell Co-stimulatory Molecules
- Dendritic Cell Development
- Flow Cytometry & Cell Selection/Detection
- Human CD Marker Products
- ICC / IHC Images: B7-2/CD86
- Macrophage Activation Markers
- Mini-review: B7 & CD28 Superfamilies
- Mini-review: B7 & CD28/CTLA-4 Receptor Families
- Mini-review: Dendritic Cell Maturation
- Mini-review: Immune Tolerance
- Mini-review: Th1/Th2
- Multiple Myeloma
- Myeloid-derived Suppressor Cells (MDSC)
- Regulatory T Cells (Tregs)
- T Cell Antigen Recognition
- Technical Notes: B7 Family Research Tools
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