Human ULBP-1 (NP 079494) VersaClone cDNA (10 UG)
货号：
RDC0804 基本售价：
2825.6 元 规格：
10 ug
产品信息
概述| 货号 | RDC0804 |
| 别名 | ALCAN-beta; MULT-1; N2DL1; N2DL-1; NKG2D ligand 1; NKG2DL; NKG2DL1; RAET1I; RAET1Ialcan-beta; Retinoic acid early transcript 1I; UL16 binding protein 1; UL16-binding protein 1 |
全称 | UL16 Binding Protein-1 | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 80329 (Human); 77777 (Mouse) |
| 背景 | ULBP-1, -2, and -3 were originally identified as ligands for the human cytomegalovirus glycoprotein UL16 and designated UL16-binding proteins (ULBP). These proteins are distantly related to major histocompatibility class I (MHC I) molecules, possessing the alpha 1 and alpha 2 Ig-like domains, but lacking the alpha 3 domain. Unlike MHC Class I, they have no capacity to bind peptide or interact with beta2-microglobulin. ULBP-1, -2, and -3 are known to bind to human NKG2D, an activating receptor expressed on NK cells, NKT cells, gamma delta T cells, and CD8+ alpha beta T cells. MULT1 (mouse UL16-binding protein-like Transcript 1) is a 53 kDa, MHC Class I-like molecule that belongs to the mouse family of NKG2D ligands. It is a type I transmembrane glycoprotein that is synthesized as a 334 amino acid (aa) precursor. It contains a 25 aa signal sequence, a 186 aa extracellular region, a 19 aa transmembrane segment and a 104 aa cytoplasmic tail. The extracellular region contains an alpha-1 and alpha-2 like domain with two intrachain disulfide bonds. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Mini-review: NKG2D and its Ligands
- Natural Killer T (NKT) Cells
- NKG2D Receptors and Ligands
|
