概述| 货号 | RDC1609 |
| 别名 | C21orf43; CD322 antigen; CD322; JAM2; JAMB; JAM-BJAM-IT/VE-JAM; junctional adhesion molecule 2JAM-2; junctional adhesion molecule B; PRO245; Vascular endothelial junction-associated molecule; VE-JAM; VE-JAMVEJAMCD322 |
全称 | Junctional Adhesion Molecule B | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 58494 (Human); 67374 (Mouse) |
| 背景 | Members of the junctional adhesion molecule (JAM) family are type I transmembrane glycoproteins of the immunoglobulin (Ig) superfamily that are localized in the tight junctions between endothelial or epithelial cells and appear to be involved in leukocyte transmigration. JAM-A, also known as platelet adhesion molecule 1 (PAM-1) and platelet F11 receptor, contains two V-type Ig-like domains, forms homodimers, and interacts with LFA-1. JAM-B (vasculoendothelial or VE-JAM) and JAM-C each contain two Ig domains (one V-type and one C2-type), a cytoplasmic PDZ-binding motif and a PKC phosphorylation site. JAM-C interacts with MAC-1 and facilitates JAM-B interaction with integrin alpha 4 beta 1. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Cell to Cell Adhesion Disassembly During EMT
- Endothelial Cell Markers and Adhesion Molecules in Angiogenesis
- Epithelial Cell Markers and Intracellular Molecules
- Epithelial Cell Polarity
- Human CD Marker Products
- Immunoglobulin Superfamily CAMs
- Surface Ectodermal Cells
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