概述| 货号 | RDC1573 |
| 别名 | erythroblast membrane-associated protein (RD and SC blood groups); erythroblast membrane-associated protein (Scianna blood group); erythroblast membrane-associated protein; erythroid membrane-associated protein; hERMAP; MGC118810; MGC118811; PRO2801; Radin blood group (Rd); Radin blood group antigen; Radin blood group; RD; RDMGC118812; SC; Scianna blood group (Sc); Scianna blood group antigen; Scianna blood group; SCMGC118813 |
全称 | Erythroblast Membrane-associated Protein | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 114625 (Human); 27028 (Mouse); 298485 (Rat) |
| 背景 | ERMAP (erythrocyte membrane-associated protein; also Scianna blood group antigen) is a 60-66 kDa member of the BTN/MOG family, Ig-Superfamily of proteins. It is expressed on erythrocytes and erythrocyte precursors and likely serves as a cell adhesion molecule. Mature human ERMAP is a 446 amino acid (aa) type I transmembrane glycoprotein. It possesses a 126 aa extracellular domain (ECD) (aa 30-155) that contains one V-type Ig-like domain (aa 30-140). Single aa changes at Gly35, Glu47, Gly57, Pro60 and Arg81 generate distinct antigens of the Scianna blood group. There is one alternate start site at Met91 and a splice variant that shows an 11 aa substitution for aa 103-475. Over aa 30-155, human ERMAP is 56% aa identical to mouse ERMAP. In contrast to human ERMAP ECD, mouse REMAP ECD contains one extra Ig-like domain. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
