货号 | RDC1578 |
别名 | 5T4 oncofetal trophoblast glycoprotein; 5T4 oncotrophoblast glycoprotein; 5T4AG; 5T4-AG; 5T4M6P1,5T4 oncofetal antigen; M6P1; TPBG; trophoblast glycoprotein | 全称 | Oncofetal Antigen/Trophoblast Glycoprotein |
反应种属 | Human |
供应商 | R&D Systems |
Entrez Gene IDs | 7162 (Human); 21983 (Mouse); 83684 (Rat) |
背景 | 5T4 (oncofetal antigen 5T4; also TPBG and trophoblast glycoprotein) is a member of the LRR family of proteins. It is expressed on trophoblasts, tumor cells, ovarian cuboidal epithelium and embryonic stem cells, and impacts cell adhesion and motility. Human 5T4 is a 72kD glycoprotein. The human 5T4 cDNA encodes a type I transmembrane protein precursor that is 420 amino acids (aa) in length. It contains a 324 aa extracellular region (aa 32 - 355) that shows one Ser-rich region followed by seven Leu-rich repeats (aa 90 - 355). Over aa 31 - 355, human 5T4 shares 81% and 85% aa identity with mouse and canine 5T4, respectively. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 |
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