概述| 货号 | RDC0965 |
| 别名 | CD107 antigen-like family member A; CD107a antigen; CD107a; LAMP-1; LAMPA; LGP120; lysosomal-associated membrane protein 1; lysosome-associated membrane glycoprotein 1; Lysosome-associated membrane protein 1 |
全称 | Lysosome-associated Membrane Glycoprotein 1 | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 3916 (Human); 16783 (Mouse) |
| 背景 | Lysosomal associated membrane protein 1 (LAMP-1), also known as CD107a and LGP120, is an approximately 120 kDa transmembrane glycoprotein that is a major protein component of lysosomal membranes. In cytotoxic T cells and mast cells, LAMP-1 is expressed in the membranes of intracellular granules that contain effector molecules such as perforin, granzymes, eicosanoids, and histamine. LAMP-1 is presented on the plasma membrane during the activation of NK cells, CD8+ T cells, mast cells, basophils, monocytes, and platelets. A glycoform of LAMP-1 known as M150 is expressed on thesurface of activated macrophages where it promotes T cell costimulation and a Th1 biased immune response. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Granulocyte Markers
- Human CD Marker Products
- ICC / IHC Images: LAMP-1/CD107a
- Isolation, Culture, and Identification of Natural Killer Cells
- Lysosomal Enzymes
- Myeloid Lineage Markers
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