Human CCR8 (NP 005192) VersaClone cDNA (10 UG)
货号：
RDC0017 基本售价：
2825.6 元 规格：
10 ug
产品信息
概述| 货号 | RDC0017 |
| 别名 | CC chemokine receptor 8; C-C CKR-8; CC-chemokine receptor chemr1; CC-CKR-8; CCR8; CCR-8; CD198; CDw198 antigen; CDw198; chemokine (C-C motif) receptor 8; chemokine (C-C) receptor 8; chemokine (C-C) receptor-like 2; Chemokine receptor-like 1; ChemR1; CKRL1; CKR-L1; CKRL1MGC129966; CMKBR8MGC129973; CMKBRL2C-C chemokine receptor type 8; CY6; GPRCL1; GPRCY6; GPR-CY6; TER-1; TER1CC chemokine receptor CHEMR1 |
| 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 1237 (Human); 12776 (Mouse) |
| 背景 | CCR8 is a G protein-coupled receptor member of the CC chemokine subfamily of receptors. Human CCR8 is 355 amino acids (aa) in length with a predicted molecular weight of 41 kDa. Mouse and rat CCR8 share 71% aa sequence identity with the human protein. Most chemokine receptors exhibit promiscuous binding properties whereby several different chemokines signal through the same receptor. Chemokine ligand receptor binding results in G protein activation as well as the activation of downstream signaling cascades, including the Akt and NFkB pathways. Chemokine receptors mediate the chemotactic actions of chemokine ligands and activation of these receptors leads to cytoskeleton rearrangement and chemotactic cell migration. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - CC Chemokines and Receptors
- Chemokine Receptors
- Chemokines and Receptors in Allergy and Asthma
- Chemokines and Receptors in Angiogenesis
- Human CD Marker Products
- Monocyte Markers
- Regulatory T Cells (Tregs)
- T Cell Migration/Adhesion
- Technical Notes: Antibodies to Complex Antigens
- Th2 Cells
- Thymocytes
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