Human B7-1/CD80 (NP 005182) VersaClone cDNA (10 UG)
货号：
RDC1086 基本售价：
2825.6 元 规格：
10 ug
产品信息
概述| 货号 | RDC1086 |
| 别名 | Activation B7-1 antigen; B7; BB1; CD28LG1; CD28LGB7-1 antigen); CD80 antigen; CD80 molecule; CD80; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; T-lymphocyte activation antigen CD80 |
| 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 941 (Human); 12519 (Mouse); 25408 (Rat); 102140078 (Cynomolgus Monkey) |
| 背景 | B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20 - 100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages. B7-2 is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - B Cell Activation
- B Cell Markers
- Common Macrophage Markers
- Control of Immune Responses via CD28 and CTLA-4
- Co-stimulatory and Co-inhibitory Molecules
- Co-stimulatory Molecules Associated with Tfh Cells
- Dendritic Cell Co-stimulatory Molecules
- Dendritic Cell Development
- Human CD Marker Products
- ICC / IHC Images: B7-1/CD80
- Macrophage Activation Markers
- Mini-review: B7 & CD28 Superfamilies
- Mini-review: B7 & CD28/CTLA-4 Receptor Families
- Mini-review: Dendritic Cell Maturation
- Mini-review: Immune Tolerance
- Mini-review: Th1/Th2
- Mouse Tissue-Resident Macrophage Markers
- Multiple Myeloma
- Myeloid-derived Suppressor Cells (MDSC)
- Regulatory T Cells (Tregs)
- T Cell Antigen Recognition
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