Human PD-1 (NP 005009) VersaClone cDNA (10 UG)
货号：
RDC0903 基本售价：
2825.6 元 规格：
10 ug
产品信息
概述| 货号 | RDC0903 |
| 别名 | CD279 antigen; CD279; hPD-1; PD1hPD-l; PDCD1; programmed cell death 1; programmed cell death protein 1; Protein PD-1; SLEB2 |
全称 | Programmed Death-1 | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 5133 (Human); 18566 (Mouse); 102123659 (Cynomolgus Monkey) |
| 背景 | PD-1 (Programmed Death-1 receptor) is a key regulator of the threshold of immune response and peripheral immune tolerance. It is expressed on activated T cells, B cells, monocytes, and dendritic cells and binds to PD-L1 or PD-L2. PD-1 ligation induces co-inhibitory signals in T cells promoting their apoptosis, anergy, and functional exhaustion. Blockade of the PD-1: PD-L1 interaction enhances anti-tumor immunity and shows potential for improving cancer immunotherapy. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - B Cell Activation
- B7/CD28 Family
- Co-stimulatory and Co-inhibitory Molecules
- Co-stimulatory Molecules Associated with Tfh Cells
- Human CD Marker Products
- ICC / IHC Images: PD-1
- ITIM/ITAM Immunoreceptors and Related Molecules
- Mini-review: B7 & CD28 Superfamilies
- Mini-review: B7 & CD28/CTLA-4 Receptor Families
- Mini-review: Immune Tolerance
- Natural Killer T (NKT) Cells
- Regulatory T Cells (Tregs)
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