Human NKp46/NCR1 (NP_004820) VersaClone cDNA (10 UG)
货号:
RDC1560 基本售价:
2825.6 元 规格:
10 ug
产品信息
概述货号 | RDC1560 |
别名 | CD335 antigen; CD335; hNKp46; Ly94; LY94lymphocyte antigen 94 homolog (activating NK-receptor; NK-p46); Lymphocyte antigen 94 homolog; MAR-1; natural cytotoxicity triggering receptor 1; Natural killer cell p46-related protein; NCR1; NK cell-activating receptor; NKp46; NKP46FLJ99094; NK-p46lymphocyte antigen 94 (mouse) homolog (activating NK-receptor; NK-p46) |
反应种属 | Human |
性能供应商 | R&D Systems |
Entrez Gene IDs | 9437 (Human); 17086 (Mouse) |
背景 | NKp30/NCR3, NKp44/NCR2, and NKp46/NCR1 are termed natural cytotoxicity receptors (NCR). These receptors are type I transmembrane proteins with 1-2 extracellular immunoglobulin domains, a transmembrane domain containing a positively charged amino acid residue, and a short cytoplasmic tail. All are expressed almost exclusively by NK cells and play a major role in triggering NK-mediated killing of most tumor cell lines. NKp44 is induced upon activation of resting NK cells with IL-2 and can bind to viral hemagglutinins. NK-mediated dendritic cell (DC) recognition is highly dependent on engagement of NKp30 and may result in lysis of the DC. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 | - Group 1 ILCs
- Human CD Marker Products
- ICC / IHC Images: NKp46/NCR1
- Isolation, Culture, and Identification of Natural Killer Cells
- ITIM/ITAM Immunoreceptors and Related Molecules
- Lymphoid Lineage Markers
- Natural Cytotoxicity Receptors (NCRs) and Ligands
- Natural Killer T (NKT) Cells
- NCR+ILC3
- NCR-ILC3
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