概述| 货号 | RDC0195 |
| 别名 | CO-029; tetraspanin 8; TM4SF3; TM4SF3tspan-8; Transmembrane 4 superfamily member 3tetraspanin-8; Tspan-8; Tumor-associated antigen CO-029 |
全称 | Tetraspanin 8/Transmembrane 4 Superfamily, Member 3 | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 7103 (Human); 216350 (Mouse); 171048 (Rat) |
| 背景 | Tetraspanin-8 (TSPAN8), also known as TM4SF3 and human tumor-associated antigen CO-0029, is a member of the transmembrane 4 (tetraspanin) superfamily. It is a cell surface 27 - 34 kDa protein with intracellular N- and C-termini, 4 transmembrane segments and a large extracellular loop (LEL) domain from aa 106 - 206. TSPAN8 is involved in integrin-mediated cell motility, metastasis, cell proliferation and differentiation, and is over-expressed in carcinomas including hepatocellular carcinoma and colon cancer. Polymorphisms have variably been associated with type II diabetes, bipolar disorder and schizophrenia. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - ICC / IHC Images: TSPAN8
- Integrins and Associated Molecules
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