Human CCR6 (NP 004358) VersaClone cDNA (10 UG)
货号：
RDC0012 基本售价：
2825.6 元 规格：
10 ug
产品信息
概述| 货号 | RDC0012 |
| 别名 | BN-1; CC-CKR-6; CCR6; CCR-6; CD196 antigen; CD196; chemokine (C-C motif) receptor 6; CKR-L3G-protein coupled receptor 29; CKRL3LARC receptor; CMKBR6STRL22; DRY6; GPR29; GPR29C-C CKR-6; GPR-CY4; GPRCY4DRY-6; lymphocyte, 22; STRL22 |
| 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 1235 (Human); 12458 (Mouse); 308163 (Rat) |
| 背景 | CCR6 is a G protein-coupled receptor member of the CC chemokine subfamily of receptors. Human CCR6 is 374 amino acids (aa) in length with a predicted molecular weight of 42 kDa. Mouse and rat CCR6 share 75% and 76% aa sequence identity with the human protein, respectively. Most chemokine receptors exhibit promiscuous binding properties whereby several different chemokines signal through the same receptor. Chemokine ligand receptor binding results in G protein activation as well as the activation of downstream signaling cascades, including the Akt and NFkB pathways. Chemokine receptors mediate the chemotactic actions of chemokine ligands and activation of these receptors leads to cytoskeleton rearrangement and chemotactic cell migration. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - B Cell Chemotaxis, Migration, and Adhesion
- CC Chemokines and Receptors
- Chemokine Receptors
- Chemokines and Receptors in Allergy and Asthma
- Chemokines and Receptors in Angiogenesis
- Dendritic Cell Adhesion and Migration
- gamma delta T Cells
- Human CD Marker Products
- LTi Cells
- Monocyte Markers
- Natural Killer T (NKT) Cells
- Regulatory T Cells (Tregs)
- T Cell Migration/Adhesion
- Th17 Cells
- Th22 Cells
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