概述货号 | RDC0615 |
别名 | delta-like 1 homolog (Drosophila); DLK; DLK1; DLK-1; FA1; FA1fetal antigen 1; pG2; pG2delta-like homolog (Drosophila); preadipocyte factor 1; PREF1; Pref-1; protein delta homolog 1; secredeltin; ZOG |
全称 | Preadipocyte Factor-1/Protein delta Homolog 1/Fetal Antigen 1 | 反应种属 | Human |
性能供应商 | R&D Systems |
Entrez Gene IDs | 8788 (Human); 13386 (Mouse) |
背景 | Pref-1 (preadipocyte factor 1), also known as deltalike 1 (DLK1) and fetal antigen 1 (FA1), is a member of the Notch/Delta/Serrate protein family. It is a transmembrane protein that can be proteolyicallycleaved to generate soluble forms. Pref-1 is believed to be a co-ligand for Notch signaling, enhancing or inhibiting Notch activation following binding of a ligand. It is expressed in numerous endocrine cells,and is highly expressed in preadipocytes, but not in mature adipocytes. In adipose tissue, Pref-1 inhibits adipogenesis and is often used as a preadipocyte marker. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 | - Adipocytokines
- Adipogenesis Markers
- Diabetes and Obesity Research
- HIF Transcription Factors
- Lipid/Cholesterol Metabolism
- Mouse Obesity Antibody Array
- Notch Family
- Notch Pathway
- Obesity
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