Human CXCR4 (NP 003458) VersaClone cDNA (10 UG)
货号：
RDC0032 基本售价：
2825.6 元 规格：
10 ug
产品信息
概述| 货号 | RDC0032 |
| 别名 | CD184; chemokine (C-X-C motif) receptor 4; chemokine (C-X-C motif), receptor 4 (fusin); C-X-C chemokine receptor type 4; CXC-R4; CXCR-4; D2S201ESDF-1 receptor; FB22; Fusin; HM89NPYRL; HSY3RR; LAP3; LCR1; LESTRCD184 antigen; Leukocyte-derived seven transmembrane domain receptor; leukocyte-derived seven-transmembrane-domain receptor; lipopolysaccharide-associated protein 3; neuropeptide Y receptor Y3; NPY3RWHIM; NPYR; NPYY3R; seven transmembrane helix receptor; seven-transmembrane-segment receptor, spleen; Stromal cell-derived factor 1 receptor |
| 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 7852 (Human); 12767 (Mouse); 60628 (Rat); 483900 (Canine); 493676 (Feline) |
| 背景 | CXCR4, also known as fusin or LESTR, is a G protein-coupled receptor (GPCR) member of the CXC subfamily of chemokine receptors. Human CXCR4 is 352 amino acids (aa) in length with a predicted molecular weight of 40 kDa. The mouse and rat proteins share 91% aa sequence identity with the human protein. CXCR4 is the chemokine receptor for CXCL12. CXCR4 is a critical regulator of progenitor and stem cell mobilization and recruitment during development and during hematopoiesis. As such, antagonists of CXCR4 can be used to harvest hematopoietic stem/progenitor cells from bone marrow. Significantly, CXCR4 also acts as a co-receptor for HIV and mediates viral entry and infection of T cells. Studies on multiple tumor types implicate the CXCL12:CXCR4 axis in tumor metastasis and angiogenesis. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Acute Myeloid Leukemia
- B Cell Chemotaxis, Migration, and Adhesion
- B Cell Markers
- Cancer Biomarkers
- Cancer Stem Cell Markers
- Chemokine Receptors
- Chemokines and Receptors in Allergy and Asthma
- Chemokines and Receptors in Angiogenesis
- Chemokines and Receptors in Tfh Cell Differentiation and Function
- CXCR4: A Receptor for Extracellular Ubiquitin
- Cytokine Upregulation of HIV Coreceptors
- Endothelial Cell Differentiation Markers
- Endothelial Progenitor and Endothelial Cell Markers
- Endothelial Progenitor Cell Markers
- gamma delta T Cells
- Hematopoietic Stem Cell Markers
- Hepatic Endoderm
- Hepatic Endoderm Cell Markers
- HIF Transcription Factors
- Human CD Marker Products
- Infectious Diseases
- Megakaryocytes
- Neural Stem Cell Markers
- Neuroinflammation
- Receptors in the Jak/STAT Pathway
- Regulatory T Cells (Tregs)
- Somite Markers
- T Cell Migration/Adhesion
- Th2 Cells
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