概述| 货号 | RDC1516 |
| 别名 | CD 150; CD150; CD150IPO-3; CDw150; IPO-3; signaling lymphocytic activation molecule family member 1; signaling lymphocytic activation molecule; SLAMCD150 antigen; SLAMF1 |
全称 | Signaling Lymphocytic Activation Molecule | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 6504 (Human) |
| 背景 | The Signaling Lymphocytic Activation Molecule (SLAM) family of receptor molecules is a subset of the CD2 family of receptors. SLAM proteins function as co-receptors for lymphocyte activation and/or adhesion and mediate tyrosine phosphorylation signals. SLAM receptor expression is mainly restricted to immune cells. SLAM, also known as CD150, is a transmembrane glycoprotein that is upregulated on activated B cells and T cells but downregulated on Th2 polarized cells. SLAM ligation promotes the activation of Th0/Th1 cells, B cells, eosinophils, mast cell, and macrophages. SLAM also functions as a cellular entry receptor for measles virus. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - B Cell Activation
- Co-stimulatory and Co-inhibitory Molecules
- Co-stimulatory Molecules Associated with Tfh Cells
- Dendritic Cell Co-stimulatory Molecules
- Dendritic Cell ITIM/ITAM Immunoreceptors
- Endothelial Cell Markers
- Hematopoietic Stem Cell Markers
- Human CD Marker Products
- ITIM/ITAM Immunoreceptors and Related Molecules
- Lymphoma
- Macrophage Activation Markers
- Megakaryocytes
- Monocyte Markers
- Natural Killer T (NKT) Cells
- Platelets
- Regulatory T Cells (Tregs)
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