概述货号 | RDC0294 |
别名 | GLP-1 receptor; GLP-1R; GLP-1-R; glucagon-like peptide 1 receptor; MGC138331 |
全称 | Glucagon-like Peptide 1 Receptor | 反应种属 | Human |
性能供应商 | R&D Systems |
Entrez Gene IDs | 2740 (Human); 14652 (Mouse) |
背景 | GLP-1 R (Glucagon-like Peptide 1 Receptor) is a class B, G protein-linked, seven transmembrane domain protein that is expressed in pancreas, lung, heart, kidney, hypothalamus, and stomach. It is a receptor for Glucagon-like Peptide, a regulator of insulin secretion by pancreatic beta cells. Drugs that target GLP-1 R are of great interest for diabetes related research. Known agonists for GLP-1 R include GLP-1, Boc5, and Cpd1. Following experiments in mouse models, GLP-1 R agonists may also useful in the treatment of acute myocardial infarction. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 | - Diabetes
- Diabetic Peripheral Neuropathy
- Glucose Homeostasis
- ICC / IHC Images: GLP-1R
- Metabolism
- Peptide Hormone G Protein-Coupled Receptors
- Protein/Peptide Hormones and Regulators
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