概述| 货号 | RDC0164 |
| 别名 | Cf2r; CF2RHTR; coagulation factor II (thrombin) receptor; Coagulation factor II receptor; F2R; HTR; PAR1; PAR1PAR-1protease-activated receptor 1; Protease-Activated Receptor 1; Thrombin receptor; ThrR; TRGPC; TRproteinase-activated receptor 1 |
全称 | Protease-Activated Receptor 1 | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 2149 (Human); 14062 (Mouse); 25439 (Rat) |
| 背景 | Human Proteinase-Activated Receptor 1 (hPAR1), also known as thrombin receptor, is a 65-70 kDa, 399 amino acid long member of the seven-transmembrane superfamily of cell-surface G protein-coupled receptors. PAR1 is activated by thrombin cleavage of its N-terminal propeptide in the extracellular domain. Human PAR1 is widely expressed in many cell types including endothelial cells, and it has been implicated in a variety of inflammatory responses. Over the regions used as immunogen, human and mouse PAR1 proteins are 58% identical in the region spanning the propeptide and extracellular domains, and 84% identical in the cytoplasmic tail. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - BMP-1 Regulation of TGF-beta Activity
- Coagulation
- Human Soluble Receptor Array Kit Hematopoietic Panel
- Human Soluble Receptor Array Kit Non-Hematopoietic Panel
- ICC / IHC Images: PAR1
- Neurotransmitter Receptors
- Neurotransmitter Receptors, Transporters, and Ion Channels
- Platelets
- Receptors in the Jak/STAT Pathway
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