概述| 货号 | RDC1290 |
| 别名 | CD210 antigen; CDw210a; HIL-10R; IBD28; IL-10 receptor subunit alpha; IL-10R subunit 1; IL-10R1; IL10RA; IL-10RA; IL10RIL-10R subunit alpha; interleukin 10 receptor, alpha; interleukin-10 receptor alpha chain; Interleukin-10 receptor subunit 1; interleukin-10 receptor subunit alpha |
全称 | Interleukin 10 Receptor alpha | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 3587 (Human); 16154 (Mouse) |
| 背景 | Interleukin-10 Receptor alpha (IL-10 R?), also known as IL-10 R1, is a transmembrane ligand-specific component of the IL-10 receptor complex. It associates with IL-10 R beta to mediate the effects of IL-10 in the control of microbial infections, allergic and autoimmune inflammation, and cancer. IL-10 R beta also associates with IL-20 R alpha, IL-22 R alpha, or IL-28 R alpha to form the receptor complexes for IL-22, IL-26, IL-28, and IL-29. Immunosuppressive signal transduction through the IL-10 receptor complex can be inhibited by activation of TLR2, 4, or 9, enabling strengthened immune responses during infection. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - B Cell Development and Differentiation
- Cytokines and Receptors in Allergy and Asthma
- Cytokines and Receptors in Angiogenesis
- Cytokines and Receptors in Tfh Cell Differentiation and Function
- Human CD Marker Products
- ICC / IHC Images: IL-10 R alpha
- IL-10/Interferon Family
- Monocyte Markers
- Neuroinflammation
- Receptors in the Jak/STAT Pathway
- Regulatory T Cells (Tregs)
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